Volatile anaesthetics attenuate hypocapnia-induced constriction in isolated dog cerebral arteries
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چکیده
منابع مشابه
Pharmacological comparison of isolated monkey and dog cerebral arteries.
Pharmacological differences between canine and monkey basilar arteries were studied in vitro. The constrictor response of canine basilar artery to either norepinephrine or an alpha 1-adrenoceptor agonist phenylephrine was partly inhibited by an alpha 2-adrenoceptor antagonist yohimbine but not by an alpha 1-adrenoceptor antagonist prazosin. The contraction elicited by an alpha 2-adrenoceptor ag...
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Methods. Changes in isometric tension were recorded in helical strips of the arteries, and the presence of perivascular nerve containing NADPH diaphorase was histochemically demonstrated. Results. Nicotine (10~ M, EOA and IOA) and transmural electrical stimulation (5 Hz, EOA) produced a slight or no contraction followed by a moderate relaxation in the strips contracted with prostaglandin F2a. T...
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REZUMAT Correspondence to: REVIEW ARTICLES CARDIOPROTECTION BY VOLATILE ANAESTHETICS: ANAESTHETIC-INDUCED PRECONDITIONING Octavian Toma, Wolfgang Schlack Precondi]ionarea anestezic\ a miocardului este un fenomen bine precizat prin care anestezicele volatile induc un efect cardioprotectiv care persist\ un anumit timp dup\ întreruperea anestezicului. Anestezicele volatile reduc necroza/apoptoza m...
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In helically-cut strips of dog cerebral, coronary and mesenteric arteries, contracted with prostaglandin (PG) F2 alpha or K+, the addition of verapamil caused a dose-related relaxation. Verapamil-induced relaxations were greater in cerebral than in the other arteries when contracted with PGF2 alpha, but did not significantly differ in the arteries contracted with K+. Similar results were obtain...
متن کاملIntegrin signaling, free radicals, and tyrosine kinase mediate flow constriction in isolated cerebral arteries.
Isolated, cannulated, and pressurized (100 mmHg) middle cerebral arteries from adult cats were perfused intraluminally at rates from 0 to 4 ml/min with heated and gassed physiological saline solution. An electronic system held pressure constant by changing outflow resistance. The arteries constricted 18.1 ± 0.95% in response to flow and depolarized from -54 ± 0.51 to -40 ± 1.26 mV ( P < 0.05). ...
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ژورنال
عنوان ژورنال: Canadian Journal of Anaesthesia
سال: 1997
ISSN: 0832-610X,1496-8975
DOI: 10.1007/bf03014465